A case series presented online in Nutrition Journal revealed that adding the amino acid N-acetylcysteine to a regimen of B vitamins administered to cognitively impaired patients with high homocysteine levels resulted in improvement in all patients. High levels of plasma homocysteine have been linked with an elevated risk of vascular disease and dementia, and have been reported in patients with mild cognitive impairment and Alzheimer's disease.

Andrew McCaddon of Wales College of Medicine in Wrexham, North Wales presented seven cases of older individuals with memory loss and/or confusion who had high plasma levels of homocysteine. "Although plasma levels of homocysteine are largely determined by vitamin B12 and folate status," Dr McCaddon writes, "Antioxidant therapy might also be required for optimal reduction in neurovascular tissue."

The five women and two men were given 600 milligrams N-acetylcysteine per day, along with treatment with oral or injectable vitamin B12 and, for most of the patients, 5 milligrams folic acid.

All seven patients experienced subjective improvement in their cognitive function after a varying amount of weeks. Objective improvement, as assessed by cognitive function test scores, was noted in five patients. One patient who underwent magnetic resonance imaging prior to receiving supplementation showed cessation of the progression of small vessel disease upon re-examination after one year of supplementation.

Dr McCaddon observed that the mechanism underlying the association with elevated homocysteine could be its adverse effects on neurovascular tissue combined with neurotransmitter synthesis impairment caused by defects in methyl group metabolism. The responses to N-acetyl cysteine demonstrated in the case series suggests that homocysteine could be a marker for the effects of oxidative stress in brain tissue.

Vitamin B12 can be found at Vitamin Depot Online.com by clicking here. Folic Acid can be found here.

In an advance online publication on February 2, 2006 in the journal Science, biologists from Brown University reported a connection between the age of baboons and the number of aging cells in their skin, boosting the theory that cellular senescence is associated with an aged body. Replicative senescence occurs when cells lose their ability to divide after a number of replications. Senescent cells are associated with skin wrinkles, weakened immune response and other age related conditions and diseases.

Professor of medical science John Sedivy and colleagues examined skin samples from the forearms of 30 baboons aged 5 to 30 for biomarkers of cellular aging. They found an exponential increase in DNA double-strand breakage with the animals' increasing age, reaching 30-35 percent in the oldest animals. The most important biomarker, telomere dysfunction-induced foci (TIF) which show that telomeres have shrunk to the extent that cell division is halted, were found in 4 percent of the tissue cells of 5 year old baboons and in up to 20 percent of the cells of the 30 year olds.

The authors observed that telomeric DNA damage may not be entirely due to replicative exhaustion, and note that oxidative stress increases the rate of telomere shrinkage.

Dr Sedivy commented, "For 40 years, we've known about replicative senescence. Whether it promotes the aging of our bodies, however, is highly controversial. While it may make intuitive sense, skeptics say 'Show us the evidence.' The first solid evidence is in this study. These initial findings won't settle the debate, but they make a strong case."

"There is good evidence that senescent cells are not benign," he added. "But until now, no one has been able to confirm that they exist in appreciable numbers in old animals."

The Experimental Biology 2004 meeting held in Washington, DC was the site of a presentation by Dr John L Zenk of the Minnesota Applied Research Center in Chanhassen, Minnesota, and Dr. Michael A. Kuskowski of the Veterans Administration Medical Center in Minneapolis, concerning the findings that 7-oxo-dehydroepiandrosterone (also known as 7-keto tm) improves immune function in older individuals. The duo presented the results of a study in which healthy adults who took the supplement twice daily for one month experienced an improvement in several T-cell mediated immune function parameters compared to those who received a placebo.

DHEA is a hormone whose decline with aging is believed to contribute to some age-associated conditions, including impairment of immune function. The decline in immune function that occurs in older individuals can predispose this population to increased susceptibility to infection and even cancer.

7-oxo DHEA is a derivative of DHEA that also declines with age and has been demonstrated to promote T-cell function in human lymphocytes (a type of white blood cell). Of the three types of immune system response, T-cell, or cellular immunity is the one in which abnormalities have been most consistently found in older individuals. People with impaired cellular immunity frequently have a less than optimal response to flu vaccination, rendering the vaccine less beneficial.

Dietary supplements such as 7-oxo DHEA may someday become widely used as immune system modulators, particularly as the older percentage of the population increases.
Protocol

DHEA Replacement Therapy
DHEA has been shown in numerous animal studies to boost immune function via several different mechanisms. Only limited human studies have been done to measure DHEA's effect on the immune system.

In one study that focused on men, scientists proposed that the oral administration of DHEA to elderly men would result in activation of their immune system: nine healthy men averaging 63 years of age were treated with a placebo for two weeks followed by 20 weeks of DHEA (50 mg a day). After two weeks on oral DHEA, serum DHEA levels increased by 3-4 times. These levels were sustained throughout the study. Compared to the placebo, DHEA administration resulted in:

* An increase of 20% in IGF-1. Many people are taking expensive growth hormone injections for the purpose of boosting IGF (insulin-like growth factor) levels. IGF is thought to be responsible for some of the antiaging, anabolic effects that DHEA has produced in previous human studies.
* An increase of 35% in the number of monocyte immune cells.
* An increase of 29% in the number of B immune cells and a 62% increase in B-cell activity.
* A 40% increase in T-cell activity even though the total number of T-cells was not affected.
* An increase of 50% in interleukin-2.
* An increase of 22-37% in natural killer cell (NK) numbers and an increase of 45% in NK cell activity.

No adverse effects were noted with DHEA administration.

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DHEA



In 1981, the Life Extension Foundation introduced DHEA (dehydroepiandrosterone) to its members through an article that described the multiple benefits that this hormone might produce. However, the general public did not learn about DHEA until 1996, when the benefits of DHEA were touted by the news media and in several popular books.

DHEA became credible to the medical establishment when the New York Academy of Sciences published a book entitled DHEA and Aging. This book provided scientific validation for the many life extension effects of DHEA.

It has been shown that the hormone DHEA often declines 80-90% by age 70 or later, leading to hormonal imbalances that can affect one’s quality of life. Peak blood levels of DHEA occur at approximately age 25, decreasing progressively thereafter. Thus, scientists have been looking at ways of restoring DHEA to youthful levels, and are now discovering mechanisms by which this hormone protects against age-related decline.

The DHEA debate
One of the most confusing issues in health care today is the role of DHEA in antiaging. While some promoters claim that it is a magic bullet that will confer heath and longevity, others state emphatically that it has no value or is actually dangerous. Consumers are left in a quandary. Concluding that it is better to be safe than sorry, millions of Americans ignore what may be one of the most important antiaging, health-sustaining substances available today.

Stephen Cherniske, MS, is a biochemist with more than 30 years of academic, clinical, and research experience. He was an adviser to members of the US Olympic team, served on the faculty of the American College of Sports Medicine, and taught clinical nutrition at the university level for over a decade. His 1996 book, The DHEA Breakthrough (Random House), was an international best-seller that helped launch the anti-aging movement worldwide.

In 1998, he was chosen to direct the Bioregenics Project, an international research effort to explore the physiology of aging. In 2001, the project was completed with an independent, double-blind, placebo-controlled human clinical trial demonstrating that the underlying causes of aging can be modified by nutrition, diet, and lifestyle.

This remarkable three-year research project forms the basis for his latest book, The Metabolic Plan (Random House, 2003). Between 1996 and 2003, Cherniske conducted hundreds of interviews and presented more than 1,000 hours of lectures to professional and lay audiences. In these interviews and scientific conferences, he encountered tremendous resistance to the use of DHEA. At the same time, more than 3,000 scientific studies on DHEA were published, leading to a clear understanding of the chemistry, function, and clinical value of this important hormone.
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The February 2006 issue of the American Journal of Clinical Nutrition published the finding of researchers at Tohoku University Graduate School of Medicine in Sendai, Japan, that consuming more green tea is associated with a lower prevalence of cognitive impairment. To the researchers' knowledge, the study is the first to examine the association between green tea drinking and cognitive function in humans.

Shinichi Kuriyama, of the school's departments of public health and forensic medicine, and colleagues evaluated data from 1002 men and women aged 70 and older who participated in the Japanese Comprehensive Geriatric Assessment in 2002. Subjects completed questionnaires concerning the frequency of green tea, black tea, and coffee consumption among other questions. Cognitive function test scores were used to classify the participants as having no impairment, slight cognitive impairment, cognitive impairment, or severe cognitive impairment.

High consumption of green tea at two or more cups per day by the top one-third of participants was associated with less than half the incidence of cognitive impairment, including severe cognitive impairment, than that found among participants whose intake was in lowest third at three or fewer cups per week. Participants whose tea consumption was in the middle third experienced a 38 percent reduction. No significant relationship between black tea or coffee consumption and cognitive impairment was observed.

The authors suggest that the lower prevalence of dementia and Alzheimer's disease in Japan could be explained by the green tea consumed by this population. "Given the high prevalence, worldwide rapid increase, and clinical significance of dementia," they write, "any association between the intake of green tea, a drink with little toxicity and no calorific value, and cognitive function could have considerable clinical and public health relevance."

—D Dye

Vitamin Depot Online.com carries a variety of Green Tea Products.

# posted by Roy Brown @ 1:07 PM 0 comments   

A study published in the February 14, 2006 issue of Circulation reported the association between the presence of cardiovascular disease risk factors at age 50 and the risk of developing cardiovascular disease over the next 45 years. The study also calculated the association between cardiovascular disease risk factors and survival.

Donald M. Lloyd-Jones, MD, of Northwestern University in Chicago and colleagues followed 3,564 men and 4,362 women who participated in the Framingham Heart Study. Participants who were free of cardiovascular disease before their initial examination between 1971 and 2002 were included in the current analysis. Cardiovascular events occurred in 1,757 participants during the follow up period ending in 2002, and noncardiovascular deaths occurred in 1,641. Lifetime cardiovascular disease risk for men and women at age 50 were calculated as 51.7 and 39.2 percent.

Optimal risk factors were defined as a cholesterol level of 180 milligrams per deciliter or lower, blood pressure less than 120/80 mm Hg, being a nonsmoker, and being nondiabetic. Having a cholesterol level of 240 milligrams per deciliter or more, blood pressure 160/100 mm Hg or higher, being a smoker, and being diabetic were considered to be major risk factors. Men with optimal risk factors had a 5.2 percent risk of developing cardiovascular disease while those with two or more major risk factors experienced a 68.9 percent risk . For women with optimal risk factors, the risk was 8.2 percent, in contrast with a 50.2 percent risk incurred by those with at least two major risk factors. Survival among men and women with optimal risk factors at age 50 was 39 years, compared to 28 years for men and 31 years for women with two or more major risk factors.

Prior to this study, lifetime risk for cardiovascular disease had not been estimated. The additional years of life associated with having optimal risk factors at age 50 should encourage younger people to achieve them.

—D Dye

The annual meeting of the American Association for the Advancement of Science in St. Louis was the site of a talk on February 17, 2006 by biologist Shripad Tuljapurkar on the possible effects of longer lifespans. Dr Tuljapurkar predicts that antiaging technologies could extend human lifespan by 20 years between 2010 and 2030. Dr Tuljapurkar, who is the Dean and Virginia Morrison Professor of Population Studies at Stanford University, stated "Some people believe we are on the brink of being able to extend human lifespan significantly, because we've got most of the technologies we need to do it."

By examining relationships between trends in aging, population growth, and economic activity in various countries, and combining the data with forecasts from researchers in the field of aging, Dr Tuljapurkar concluded that "Starting around 2010, we could see lifespan increase dramatically."

The extension of average lifespan in industrialized countries from 80 to 100 years reflects a growth rate in human lifespan that is five times the current rate. Although this will boost global population, creating a number of challenges, a longer lived population could be the solution to the population decline forecasted for countries with low fertility rates. Dr Tuljapukar predicts that the extension in lifespan will occur in wealthier countries in which people can afford antiaging technologies, leaving poorer countries behind. "Big pharmaceutical companies have a well-established track record of being very difficult when it comes to making things available to those who can't pay for them," he observed.

"What we've tended to do historically with medical advances is to take the reasonable position that we should implement everything that comes along," Dr Tuljapurkar concluded. "However, we are now approaching a stage where it's necessary to look the implications before we rush in--at least so we can prepare ourselves."

—D Dye

Research published in the February 15, 2006 issue of the journal Free Radical Biology and Medicine found that supplementing smokers with vitamin C can halt the depletion of vitamin E that occurs in this population. Vitamin E offers protection to the lungs from free radicals created by smoking, but can itself be transformed into a destructive free radical without adequate vitamin C.

Prior to the double-blind trial, researchers at the Linus Pauling Institute at Oregon State University asked 11 smokers and 13 nonsmokers to consume a diet containing low amounts of fruits and vegetables for three months to create a vitamin C depleted state. Participants were then given 500 milligrams vitamin C or a placebo twice daily for two weeks. The team found that smokers who received vitamin C had a plasma vitamin E disappearance rate similar to that of nonsmokers, but those who received a placebo and were therefore deficient in vitamin C lost the form of vitamin E known as alpha-tocopherol 25 percent more rapidly than nonsmokers and gamma-tocopherol about 45 percent faster.

The research is the first to demonstrate this interaction between the vitamins in humans, and could help explain how smoking causes cancer. Lead researcher and OSU professor of nutrition Maret Traber stated, "A lot of nutrition research in the past has been done by studying one nutrient or another in isolation, sometimes with conflicting results. What this and other studies like it are showing is that the protection we get from proper diet or supplements often comes from combinations of nutrients working together. This has implications not only for smokers but also for many other people."

Dr Traber also noted that many studies showing "no benefit" from vitamin supplements have been done in people with existing disease, but for antioxidants to be successful, they usually have to be present in advance.

—D Dye

Vitamin Depot Online Offer's Vitamin C supplements, along with other supplements to help your body.

The April 2006 issue of the International Journal of Cancer published the findings of researchers from Roswell Park Cancer Institute in Buffalo, New York that supplementing with selenium significantly reduced the risk of colorectal adenomas (polyps) among smokers or those whose levels of the mineral were low. Polyps can be a precursor to colorectal cancer (CRC).
The study population consisted of participants in the Nutritional Prevention of Cancer trial follow up who were randomized to receive a 200 microgram per day selenium supplement or a placebo for an average of 7.9 years. Plasma selenium levels, body mass index and smoking status were ascertained upon enrollment. Five hundred ninety-eight subjects received one or more sigmoidoscopic or colonoscopic examinations during the follow up period. There were 99 adenomas found during the initial examinations, which were classified as prevalent, and 61 identified at subsequent examinations, classified as incident.
For prevalent and incident adenomas, there was a slight reduction in risk associated with selenium supplementation among all participants. Current smokers were more likely to have adenomas than those who never smoked. When current smokers were separately analyzed, there was a significant 73 percent reduction in risk found among those supplemented with selenium compared to those who received the placebo. When the participants were divided into thirds according to baseline plasma selenium status, those whose levels were in the lowest third and who received selenium rather than a placebo, also experienced a 73 percent reduction in risk.
Several mechanisms may be responsible for a chemopreventive effect of selenium against colorectal adenomas, such as depression of carcinogen bioactivation, cell proliferation and cell cycling, and an increase in programmed cell self-destruction.
The authors conclude, "These data show that selenium supplementation is associated with a decrease in prevalent adenomatous polyps, particularly in current smokers and subjects with a low baseline plasma selenium level. The chemopreventive effects of selenium supplementation appear [to] impact both the formation of colorectal tumors and the premalignant lesions for CRC. Prospective studies specifically designed to test the chemopreventive efficacy of selenium supplementation on CRC and adenoma incidence are needed to confirm these results."





Super Selenium Capsules
As an essential cofactor of glutathione peroxidase 73 , selenium is an important antioxidant. It is also involved with iodine metabolism, DNA repair 75 , immune function, and the detoxification of heavy metals. High doses of vitamin C (over 1 gram) may reduce the absorption of selenium. This mineral is best taken one hour before or 20 minutes after taking vitamin C supplements.
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Colorectal Cancer
There is a direct relationship suggested by epidemiological studies between total fat intake in the diet and increased risk of cancer in the colon and rectum. Animal fat, particularly dairy products, and red meat are associated with colon cancer risk, whereas there is no association with vegetable fats, and fish oils appear to have a protective effect (Schloss et al. 1997). Lower cholesterol levels have been shown in patients diagnosed with colorectal cancer (Forones et al. 1998). Conversely, elevated levels of serum triglycerides have been associated with a higher risk of adenomatous polyps (Bird et al. 1996b).
The risk factor associated with alcohol consumption and cigarette smoking is startling. Daily alcohol intake has been associated with a twofold increase in colon carcinoma (Giovannuci et al. 1998). Smoking is an independent risk factor and long-term smoking is particularly damaging, increasing the relative risk by 1.6-4.5 fold for adenoma formation (Nagata et al. 1999) Smoking more than 20 cigarettes a day increases the likelihood of having polyps by more then 250%, while alcohol consumption increases likelihood by 87%. When combined, smoking and alcohol consumption increase the likelihood by an astonishing 400% (Martinez et al. 1995; Lieberman et al. 2003).
Increased vitamin D intake has been associated with reduced risk for colon carcinoma (Garland et al. 1999). Vitamin D3 causes differentiation of colon cancer cells. Cancer cells that are well differentiated are close to the original normal healthy colon cells in nature and are usually less aggressive cancer cells. Poorly differentiated cells have changed more from the normal healthy cells and are usually more aggressive cancer cells.
In high-risk individuals, the use of multivitamins has been shown to reduce the risk of adenoma formation (Whelan et al.1999). A reduced risk of colon cancer is associated with the use of vitamin C (Howe et al. 1992). Vitamins C, E, and A showed protection against the risk of developing colorectal cancer (Newberne et al. 1990). Low levels of selenium correlated with the presence of adenomas (benign tumors), whereas increased levels were associated with reduced risk of adenomas (Russo et al. 1997). Intervention trials have found a beneficial effect of selenium supplementation. There is an association between iron exposure and colorectal polyps (Bird et al. 1996a).


Calcium Citrate with Vitamin D Capsules
Calcium is an essential mineral that is often inadequately supplied, inefficiently absorbed, or excreted faster than it is being assimilated. The citrate salt of calcium has been documented to be well absorbed and utilized by the body. Get yours today!Calcium Citrate 300 Capsules

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Do Cherries Prevent Cancer?

In a warning letter to Friske Orchards of Ellsworth, MI, the FDA recites the following information contained on this orchard’s website:38

“Tart cherries may reduce the risk of colon cancer because of the anthocyanins and cyanidin contained in the cherry.”

The FDA goes on to say in its warning letter:

“These claims cause your product to be a drug as defined in section 201(g) . . . Because this product is not generally recognized as safe and effective when used as labeled, it is also defined as a new drug in section 201(p) . . . Under section 505 of the Act (21 USC 355), a new drug may not be legally marketed in the United States without an approved New Drug Application . . .”

As you will read in the article titled “Why Is the FDA Picking on Cherries?” we reveal the data that substantiate the cancer-preventive and other health benefits that scientists have discovered about cherries.

Interestingly, the FDA is not denying the veracity of this information. Instead, it insists that a new drug application has to be approved before the public can be informed about the scientific data supporting cherries. The FDA also asserts, without any basis, that cherries “have not been recognized as safe and effective when used as labeled.”38 According to the FDA’s interpretation of the law, cherry growers are engaged in criminal conduct by relaying findings that have been published in peer-reviewed scientific journals. Whether you or other Americans develop cancer does not appear to be a consideration of an agency whose written mission statement includes the following:

“The FDA is responsible for advancing the public health by helping to speed innovations that make medicines and foods more effective, safer, and more affordable; and helping the public get the accurate, science-based information they need to use medicines and foods to improve their health.”39

As Life Extension documented many years ago, the FDA does the opposite of what it pretends to do. Instead of “helping the public get the accurate, science-based information they need to use foods to improve their health,” the FDA has gone to extreme lengths to deny American citizens the right to learn about scientific studies substantiating the health benefits discovered about cherries (and other fruits).

As an essential cofactor of glutathione peroxidase 73 , selenium is an important antioxidant. It is also involved with iodine metabolism, DNA repair 75 , immune function, and the detoxification of heavy metals. High doses of vitamin C (over 1 gram) may reduce the absorption of selenium. This mineral is best taken one hour before or 20 minutes after taking vitamin C supplements.

Vitamin Depot Online.com offers Super Selenium along with other vitamins.

The Astronomical Cost of Hangovers

A study in Annals of Internal Medicine compiled the enormous cost of lost productivity induced by hangovers (Wiese et al. 2000). Here is an excerpt from this study:

The alcohol hangover is characterized by headache, tremulousness, nausea, diarrhea, and fatigue combined with decreased occupational, cognitive, or visual-spatial skill performance. In the United States, related absenteeism and poor job performance cost $148 billion annually (average annual cost per working adult, $2000). Although hangover is associated with alcoholism, most of its cost is incurred by the light-to-moderate drinker. Patients with hangover may pose substantial risk to themselves and others despite having a normal blood alcohol level. Hangover may also be an independent risk factor for cardiac death.

Based on these statistics, hangover causes a significant economic loss in the United States. The staggering cost of alcoholic hangover could be significantly mitigated if drinkers took the right antioxidants before going to bed.

Note: Alcohol depletes many vitamins and minerals from the body, so taking high-potency vitamin-mineral supplements throughout the day is very important.


The Anti-Alcohol Antioxidant formula, GastroPro, Kyolic Garlic Formula 105, S-adenosylmethionine (SAMe), TMG, folic acid, vitamin B12, Silibinin Plus, Life Flora (probiotic), Nutra Flora, and magnesium can be obtained from Vitamin Depot Online.com by calling (239) 404-2525 or by ordering online. Vitamin Depot Online.com can also refer you to suppliers of offshore medications such as Picamilon and Pyritinol.

# posted by Roy Brown @ 8:07 AM 0 comments   

In recent years, the beneficial effects of genistein and other soy isoflavones have been shown in numerous published studies. These studies reveal that those who consume the most soy maintain healthier cell colonies.

Other constituents of soy have also demonstrated effects that help explain the health and longevity of Asian populations who consume a great deal of soy in their diet. In response to increasing evidence that other constituents of soy may provide significant cell protective effects, a new formulation has been developed that provides the same standardized isoflavone extract that members have been using for the past seven years, plus fermented soy natto that may provide additional benefits.

Vitamin Depot Online.com offers Soy Isoflavones, along with other supplements that will help extend your life.

This novel fiber blend may not only facilitate the weight-loss effects of diet and exercise, but also help protect against a host of health problems in which excess insulin is a significant culprit.

The patent-pending PGX™ formula is the result of hundreds of tests designed to create a highly viscous fiber that helps maintain a healthy balance of some carbohydrates in the gastrointestinal tract before they are assimilated into the bloodstream.

This supplement should be taken in conjunction with a healthy diet and regular exercise program. Results may vary.

Purchase PGX Soluble Fiber Blend and other weightloss supplements at Vitamin Depot Online.com

Scientists have identified specific extracts from cruciferous vegetables (broccoli, cauliflower, Brussels sprouts, etc.) that modulate hormones in a way to help maintain healthy cell division.

The glucosinolates are major constituents of cruciferous vegetables that have been shown to promote normal apoptosis and induce the expression of the beneficial p53 gene via an estrogen-independent action.

Watercress contains isothiocyanates, but in a broader spectrum than does broccoli. The primary isothiocyanate precursor (PEITC) in watercress functions via four specific mechanisms to maintain healthy cell division. Extracts from rosemary enhance liver metabolism of estradiol and estrone, inhibits the formation of DNA adducts, and have been shown to impede estrogen-induced growth promotion in certain tissues.

Vitamin Depot Online offers the Dual-Action Cruciferous Vegetable Extract, along with many other health supplements.

For nearly 2800 years the Chinese have used extracts from the Ginkgo biloba tree to treat a variety of conditions to maintain the healthy normal function of the brain, cardiovascular, blood and blood vessels, circulatory, and metabolic processes.

Ginkgo may:

Help to maintain normal circulation

Help to maintain the normal function and tone of blood vessels

Maintain oxygen and glucose metabolism in the brain

Prevent capillary fragility and blood leakage into surrounding tissue

Help the normal function of factors that maintain a normal blood flow

Maintain normal coagulation of blood

Reduce tissue damage caused by low blood flow

May help control radiation-induced brain edema in-vitro

Help slow the aging process in the brain

Find Ginkgo Biloba Certified Extract at Vitamin Depot Online, along with other health products.

# posted by Roy Brown @ 4:54 PM 0 comments   

A problem overlooked by most doctors is that loss of bone density is associated with deficiencies of not just calcium, but a host of other nutrients including magnesium and vitamin D3. In order for calcium to prevent bone loss, adequate amounts of vitamin D3, zinc, manganese and other nutrients should be available so that calcium, magnesium, and phosphorus can be incorporated into the bone matrix. Another issue that many people are not aware of is that many forms of calcium do not absorb particularly well.

In order to overcome the impediments that preclude aging women from achieving optimal calcium status, a mineral formula has been designed that provides 1200 elemental milligrams of a new highly absorbable form of calcium per daily dose, along with critically important nutrients needed to protect bone density. Bone Restore™ provides calcium along with nutrients like boron and silicon to further boost the body’s ability to maintain healthy bone density.

Bone Restore™ provides calcium along with nutrients like boron and silicon to further boost the body’s ability to maintain healthy bone density.

Anxiety and Stress

Aromatherapy
Studies on the use of aromatherapeutic massage show it has a mild, transient anxiety-reducing effect (Cook et al. 2000). Aromatherapeutic massage involves adding 10-12 drops of essential plant oil to 1 oz of carrier oil such as almond oil. Calming scents include lavender, neroli, lemon balm, chamomile, geranium, and clary sage. You can also add 10 drops of an essential oil to a warm bath. The benefits aren't sufficient to cure anxiety or stress alone, but regular massage is a good way to relax and reduce stress.


Center Your Mind
Meditation relaxes body, mind, and spirit. A variety of techniques can induce a meditative state: silently repeating a mantra or a prayer, gazing at a lit candle, or focusing on your breathing. Research confirms that two types of meditation can relieve anxiety: Transcendental Meditation (TM) and mindfulness. TM is a simple and effortless way to quiet the mind and deeply relax the body. In a nutshell, you sit in a comfortable position with eyes closed and silently repeat a mantra (a meaningless, simple sound). Ideally, do this for 15-20 minutes morning and evening. Research shows that other benefits of this type of meditation include reduction in blood pressure, pain, and insomnia.

In one study, a group of 83 African-Americans were assigned to learn (1) TM, (2) progressive muscle relaxation, or (3) cognitive behavioral strategies. At follow-up testing one year later, both the meditation and the progressive muscle relaxation groups showed significant increases in overall mental health and decreases in anxiety (Gaylord et al. 1989).

Mindfulness is an ancient Buddhist meditation practice with a goal of full awareness of the present moment, without becoming distracted by thoughts of the past or future. In theory, this sounds simple; in actuality, maintaining this state of mind requires effort and discipline. As noted earlier, the results of McCraty et al. (1998) suggest that people do have greater control over their overall health than previously recognized and that they can learn techniques to "reprogram" how they respond to situations so that they experience lower stress levels, fewer negative emotions, and an increased positive lifestyle. Kabat-Zinn (1990, 1994), author and the founder and director of the Stress Reduction Clinic at the University of Massachusetts Medical Center in Worcester, has conducted studies showing that mindfulness meditation can reduce stress and anxiety.

In 1992, he showed that a mindfulness meditation program reduced anxiety and panic in people with generalized anxiety disorder, panic disorder, and panic disorder with agoraphobia (Kabat-Zinn 1992). In 1995, Kabat-Zinn and colleagues followed up on this original group of 22 patients and found that the majority of them continued the meditation practice and that it had long-term benefits in reducing anxiety and panic attacks (Miller et al. 1995). Shapiro et al. (1998) found that mindfulness meditation reduced stress and anxiety among premedical and medical students.
References

Product Availability from Vitamin Depot Online.com

Adapton, melatonin, DHEA, theanine, Life Extension Mix, Sports Ginseng, and calcium-magnesium formulas are available

References

Innovative Research and Applications for CoQ10
By Kurt J. Samson

CoQ10 and the Brain
A study conducted by research-ers at Columbia University College of Physicians and Surgeons in New York found CoQ10 deficiency in the brains of 17 patients with cerebellar ataxia and/or atrophy, suggesting an ataxic syndrome responsive to therapy with the supplement.18 The scientists examined the distribution of CoQ10 in different brain regions in animals and in one human subject before and after administering CoQ10 supplements. In experimental rats, the lowest levels of CoQ10 were found in the cerebellum, but the relative proportion was similar in the blood, organs, and tissue.

In the human subject, daily supplementation with CoQ10 increased levels in the blood and liver, but CoQ10 levels in the brain remained low in four brain regions.

Nonetheless, the findings suggest “selective vulnerability” in the cerebellum to CoQ10 depletion and its protective mechanisms, according to Drs. Ali Naini and Salvatore DiMauro.

Macular Degeneration
In the journal Ophthalmologica, Dr. Janos Feher, a researcher at the University of Rome, Italy, reported that CoQ10 may improve retinal function in patients with age-related macular degeneration by improving the performance of mitochondria in the retinal pigment epithelium.19

Dr. Feher and associates treated 14 patients diagnosed with early age-related macular degeneration using a preparation that included CoQ10, acetyl-L-carnitine, polyunsaturated fatty acids, and vitamin E. A matched control group received vitamin E alone. A number of tests were then performed at 3, 6, 9, 12, and 24 months.

In patients receiving the CoQ10 mixture, all functions were slightly improved after three months and remained level throughout the two-year study period, while degeneration and visual function among participants in the control group continued to slowly decline.

Parkinson’s Disease
In a study of Parkinson’s disease patients, 360 mg a day of CoQ10 was administered for only four weeks, producing a mild symptomatic improvement compared to placebo. More important, an established clinical test to measure Parkinson’s symptom function showed significantly better improvement of performance in the CoQ10-supplemented patients compared with the placebo group.20

This new study helped to corroborate a report last year that Parkinson’s patients consuming 1200 mg a day of CoQ10 showed a 44% reduction in the decline of motor skills, movement, and mental function compared to the placebo group. Those receiving this high-dose CoQ10 also demonstrated an improved ability to perform daily living tasks. This 16-month study was remarkable in that CoQ10 slowed the progression of the disease, something that Parkinson’s drugs do not do.21

Conclusion
As the many studies outlined in this article show, biomedical researchers are discovering that CoQ10 shows promising effects against disorders as far-ranging as kidney failure, heart disease, muscular dystrophy, and macular degeneration. Despite the ever-growing number of clinical trials attempting to unlock CoQ10’s disease-preventing capabilities, widespread acceptance of CoQ10 by mainstream medical practitioners and federal health regulators continues to lag far behind the research findings. As larger and more varied studies of CoQ10 are undertaken and the results disseminated, the day when this critical nutrient gains the attention it deserves appears to be drawing ever nearer.
(reference)

VitaminDepotOnline can help you choose the CoQ10 that is right for you. Visit our website to learn more about the supplements we offer.